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- ArticleOdegaard A, Ophus EM, Larsen AM.J Clin Pathol. 1978 Sep;31(9):893-6.Thirty-two years after injection of thorium dioxide (Thorotrast) for diagnostic x-ray studies in a female patient deposits were found by light microscopy in the liver macrophages (Kupffer cells). They were shown by electron microscopy to be located inside secondary lysosomes, and by autoradiography and x-ray microanalysis they were identified as thorium.